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Created in Japan and first registered in 2005, Coluracetam is a very new and very important entry in the world of noots.
It is, thus far, the only known HACU(high affinity choline uptake) enhancer; HACU is the rate-limiting step at which acetylcholine can be produced within neurons, and this rate-limiting enhancement literally overclocks the cholinergic system, like jumping a broadband cap.
It has AMPA-like effects, and has been seen to reduce excitotoxicity due to glutamate/calcium influx as well as negate many cholinergic neurotoxins, which suggests a use for the Alzheimers spectrum and general learning disabilities due to its ACh preservation.
Human anecdotal reports include increased short/medium-term memory & visual/audial acuity, as well as motivation, focus/awareness and mood boosts.
Once taken regularly for roughly 2 weeks, improvements have been seen to persist for up to 72 hours after the last dose taken.
CDP(Cytidine DiPhosphate) Choline, also known as Citicoline, is a highly bioavailable choline-containing phospholipid Nootropic compound that dissociates in-vivo into the compounds Choline and Cytidine, the latter of which is then quickly converted into Uridine, one of the four basic components of RNA(Ribonucleic Acid). The benefits of taking CDP compared to a lesser choline source is that it provides the body with enough raw choline along with cofactors for various (*)choline esters to both facilitate neurotransmitter production(via (*acetyl)choline) AND strengthen neuronal membrane integrity(via (*phosphatidyl)choline), by removing unnecessary steps in various cholinergic syntheses and keeping the body from cannibalizing one process for another due to limited available materials to work with.